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Chemogenetic stimulation of GLP-1Rexpressing POMC neurons reduced food intake in mice (126), while GLP-1R knockout in POMC neurons did not attenuate the acute anorectic effect of Ex-4, although it is possible that developmental compensation may account for the lack of effect in this model (45)

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Risk of Hyperpigmentation/Burns Because RF skin tightening works by delivering thermal energy into the dermal layers, the increased melanin in the skin due to Melanotan can lead to over-absorption of heat in the epidermis

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prepared liposomes with BA as the main component and borneol and cholic acid as additives