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The complete reduction of oxygen can be seen from the steps outlined below[4]

Supports against oxidative stress

During exposure to MPs and NPs, these immune markers exhibit a biphasic, concentration-dependent response: their levels initially increase but subsequently decline upon prolonged or high-dose exposure, indicating that excessive stress may lead to immune exhaustion or suppression

We can see several possibilities, which are not mutually exclusive

These novel delivery strategies not only enhance drug bioavailability but also offer sustained release and improved patient compliance, which are essential for effective treatment of cerebral ischemia