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The range applies when there is reason to expect a depleted baseline age 50+, recovering from chronic illness or a post-viral state, prolonged caloric deficit, chronic stress, or symptomatic fatigue at protocol start

This dual action could lead to more weight loss than medications targeting GLP-1

Also, expanding regulatory approvals for obesity indications have reinforced this segments dominance

The number of Medicaid prescriptions and gross spending on GLP-1s have increased substantially since 2019 (Figure 2)

Concurrent Medications Because semaglutide slows gastric emptying, it may affect the absorption of some oral medications

It is a peptide similar to the hormone glucagon-like peptide-1, modified with a side chain