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After 12 weeks, the researchers noted the following weight changes in the two groups: [table id=356 /] The following blood work changes were also found in the two groups: [table id=357 /] For the researchers, 12 weeks of carnitine administration in women with polycystic ovary syndrome resulted in reductions in weight, body mass index, weight circumference, and hip circumference, and beneficial effects on blood sugar control though they admit that Further long-term studies with higher doses of carnitine are needed to examine the effect of carnitine supplementation on markers of insulin resistance, lipid profiles and hormonal outcomes in polycystic ovary syndrome patients. * HOMA RI is used as a screening test for glucose intolerance

10.1016/j.fgb.2016.10.006 90 SzklarczykD.KirschR.KoutrouliM.NastouK.MehryaryF.HachilifR.et al

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So, its entirely possible GIP receptor agonism acts the same way as GIP receptor antagonism because its desensitizing receptors over an extended period of time