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19-22 With the exception of linagliptin, the DPP-4 inhibitors are primarily cleared by the kidneys and, thus, require renal dose adjustment

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(And dont forget to consult your healthcare professional before you try any new supplement.) The following supplements have some of the strongest evidence for kicking migraine symptoms to the curb or preventing them before they begin, but its always important to speak with your doctor before adding a supplement to your treatment plan