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Am J Physiol Regul Integr Comp Physiol (2014) 306(11):R8617.10.1152/ajpregu.00533.2013 191 OropezaDJouvetNBouyakdanKPerronGRinguetteLJPhilipsonLHet alPGC-1 coactivators in -cells regulate lipid metabolism and are essential for insulin secretion coupled to fatty acids

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If weight changes during perimenopause are part of your picture, it's worth asking your provider whether both programs are worth exploring simultaneously