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24 Large observational cohort studies have also demonstrated significantly lower rates of fatal and nonfatal cardiovascular events in individuals undergoing bariatric surgery

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This fact predestines CSF to be that sample type from living subjects to analyze CNS-related exposure, transport efficiency across neural barriers or metabolic changes in the brain due to neurodegenerative conditions (Solovyev et al., 2013)

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In addition to the elevated blood pressure readings obtained from the sphygmomanometer, patients with hypertension often experience other issues such as endothelial dysfunction, increased peripheral vascular resistance, and arterial stiffness