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Doses ranging from 1.5 to 3 grams per day for at least three months consistently show improvements in cognitive function several-fold greater than placebo, with significant improvements in attention, memory, and intellectual functioning

It is a progressive disease and, if left untreated, may lead to liver disease, central nervous system dysfunction and death[2,3]

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They also reported that the expression of SOCS3 protein was clearly reduced in senescent M2 macrophages which probably aggravated STAT3 signaling

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