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GFAP is a robust marker of cerebrovascular damage and is elevated after repetitive head trauma, reflecting BBB disruption, as seen in contact sport athletes and in individuals with self-reported neurological symptoms in long COVID 26,52,53

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[8] Serious side effects may include angioedema, low blood sugar, kidney problems, pancreatitis, and joint pain

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Additionally, limited supply of pharma-grade and plant-based variants has caused distribution challenges, requiring advanced supply chain management and capacity expansion strategies