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7 Following strong clinical trial results, higher-dose versions of Ozempic and Mounjaro, called Wegovy and Zepbound, respectively, have been approved for obesity by the FDA

Some patients also ask about stretching a prescription with lower doses, which saves money but has no trial support

The benefit of SGLT2i therapy beyond improved glycaemic control was first reported in the EMPA-REG study which reported a reduced incidence of major adverse cardiovascular events in patients with type 2 diabetes [19]

There are multiple drug names and mechanisms, ongoing debates about who should take the drugs, questions about cost and access, and anxiety about what happens if you stop taking them

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Clozapine directly increases insulin and glucagon secretion from islets: implications for impairment of glucose tolerance