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The first phase in the table covers drug clearance beginning, appetite potentially returning, and nausea typically resolving, with fasting glucose and insulin listed as the markers to watch

This means the 10 to 200 mcg/kg doses that dominate the animal literature translate to a rough human equivalent of approximately 1.6 to 32 mcg/kg, or about 120 to 2,400 micrograms for a 75-kilogram adult

For older adults, caution is advised due to the higher likelihood of underlying health conditions or medication use that might interact with the peptide

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