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You can read more on dose targets in Vitamin C Dosage and Safety

It needs a major overhaul

Restored desire PT-141 activates arousal pathways in your brain

Phua, T.J., Rogers, T.R., and Pallett, A.P

But if you are still not losing weight after having reached the appropriate dosage, you may be a nonresponder

Before starting a vitamin B12 supplement, consult a doctor or nutritionist who can determine whether supplementation is needed and recommend the appropriate dose