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At therapeutic doses, GLP-1 drugs cross the blood-brain barrier and dampen dopamine signaling in the brain's core reward center, making addictive substances less rewarding

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GLP-1R agonists have been thought to be an excellent candidate due to their pleiotropic effects on the gutbrain axis

Slower Gastric Emptying Food may move through the stomach more slowly, which can influence fullness for some patients

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Gonzlez-Crdova, B