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FAMILY HISTORY - More than half have family members with gallstones who ultimately required cholecystectomies

And they escalate if you ignore them

Anna Lembke, a Stanford University addiction medicine specialist, told The Associated Press that while some clinicians are already prescribing GLP-1s off-label for addiction, the drugs dont work the same way for everyone and carry risks, including gastrointestinal side effects, pancreatitis and kidney conditions, that must be weighed

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10.6118/jmm.2015.21.2.93 30 LiY.FuH.WangH.LuoS.WangL.ChenJ.et al (2020a)