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This is exactly the phenotype in which targeting oxidative stress and inflammation is conceptually most rational

Holohan C, Van Schaeybroeck S, Longley DB, Johnston PG

Specifically, they activate the AMPK/PPAR- signaling axis, which reduces fibroblast proliferation and myofibroblast differentiation in fibrotic models [197]

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What Does the Preclinical Evidence Show

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