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As a result, folate deficiency can lead to many neuropsychiatric manifestations, such as depression, alterations in neurotransmitter function, DNA damage, as well as being associated with the development of autism spectrum disorders in children, neural tube irregularity and brain development defects (4, 19, 20, 22, 30, 66, 68, 69)

10.1016/j.febslet.2010.01.017 77 KaczmarekA.VandenabeeleP.KryskoD

Contraindications Hypersensitivity to Glutathione

Acknowledgments We gratefully acknowledge Sara Caturani for her outstanding artwork contributions to this article

Brief Communication scavenging effects of tea catechins and their derivatives on l,l-diphenyl-2-picrylhydrazyl radical

In a similar study, the pivotal role for the IGF-1 in insulin sensitivity has received further support from liver-specific IGF-1 KO mice which exhibited overt insulin resistance and hyperinsulinaemia that was reversed by the administration of IGF-1 [161]