Indirectly, through weight loss: as visceral fat shrinks, 11-beta-HSD1 activity drops, free fatty acids fall, and insulin sensitivity improves
Less common but serious side effects include pancreatitis, gallbladder issues, and (in rare cases) thyroid tumors in patients with a personal or family history of medullary thyroid cancer or MEN-2
10.1016/S0899-9007(00)00421-4 58 LarsenP
Who It Is For Patients with stubborn visceral fat that resists diet and exercise Men and women experiencing metabolic slowdown associated with aging Patients with insulin resistance or metabolic syndrome who want to improve metabolic markers Anyone seeking meaningful body recomposition not just weight loss, but shifting the ratio of fat to lean mass Patients who have plateaued on a weight loss program and need a metabolic reset What to Expect Weeks 1-4: Improved energy and exercise tolerance as mitochondrial function improves
Lipids and Triglycerides Cholesterol and triglycerides should not be ignored during GLP-1 treatment
Addition of a His-tag is indicated with light blue
