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There may still be limited use under 503A compounding rules, where a medication is prepared for an individual patient based on a specific clinical indication, but that pathway is much more restricted and not designed for widespread use. Jen Manne-Goehler, MD, ScD,assistant professor of medicine at Harvard Medical School, agreed

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The standard shelf life for reconstituted tirzepatide with bacteriostatic water is 28 days, with some sources extending this to 60 days under ideal refrigeration conditions

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However, older adults are also more likely to be taking multiple medications, and peptide interactions with common medications for hypertension, diabetes, and cardiovascular disease have not been systematically studied

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