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The clinical trial is designed to enrol approximately 115 participants

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Surgery GLP-1 drugs mimic at least one hormone produced by the gut to signal fullness, leading to a reduced appetite

Some remain at 8 mg long-term, while others reach and tolerate 12 mg comfortably

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The peptide shares approximately 48% amino acid sequence homology with insulin and binds to insulin receptors, though with lower affinity than insulin itself