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Zhou et al.s study showed that increased BCAA intake promoted insulin resistance in ob/ob mice, an effect associated with inflammatory activation (78), suggesting bidirectional regulation between inflammation and BCAA metabolism

2021LPTD-004), Natural Science Foundation of Shanghai (grant nos

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In the present case, epiploic appendagitis occurred in temporal association with substantial and relatively rapid weight loss during tirzepatide dose escalation, consistent with the hypothesis that physiologic changes accompanying weight reduction may have influenced susceptibility, although causality cannot be inferred

Investigation of drug interactions