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Actual payment is calculated by multiplying total RVU by the geographic adjustment factor and the CMS conversion factor for that payment year

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Among them, compound 8u becomes the most effective xanthine oxidase inhibitor, with an IC50 value of 0.0288 mM, which is equivalent to febuxostat (IC50 0.0236 mM) (Zhang et al., 2019)

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Other reasons for depleted levels include a diet lacking fruit and vegetables, stress, lack of sleep, alcohol intake, chronic disease and infection