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Table 2 Summary of the main studies with GLP1-AR

While war interrupted Zuelzer's work, it did not prevent others from continuing to investigate the use of pancreatic extracts for diabetes elsewhere

5 Discussion GLP-1RAs have emerged as a paradigm-shifting class of agents, with therapeutic benefits that extend well beyond glycemic control in type 2 diabetes

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GLP-1 receptor agonists reduce glucagon and glycogen secretion, inhibit appetite and slow gastric emptying [17] [18], creating a multifaceted approach to weight management that addresses both metabolic and behavioral components of obesity