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It is more stable than the reduced form and is not oxidized in the gastrointestinal tract

& Pichumani, M

These can sometimes lead to dehydration, which may strain the kidneys

[55] reported that semaglutide treatment caused weight loss and a lesser decrease in energy expenditure as compared with placebo in calorie-restricted, weight-matched rodents

doi: 10.1016/j.ejphar.2015.11.004 40 GlatzJFLuikenJJ