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In its active form, the peptide binds divalent copper ions (Cu), with the histidine residue serving as the primary coordination site
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Always use fresh sterile supplies for each reconstitution and each dose drawing session
Replenishing the nutritional status of the host by increasing vital amino acids such as cysteine to enhance GSH levels and selenium to improve selenium deficiency and facilitate selenoprotein (GSH peroxidases, thioredoxin reductases) expression can inhibit oxidative stress, modulating inflammation, suppressing endothelial dysfunction, and protecting vascular cells against apoptosis and calcification (He et al., 2017
et al., 2020)