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This understanding is in line with the chronotropic effects of GLP-1 RA treatment, which in a large meta-analysis was shown to be associated with heart rate increases of up to 3.35 beats/min (Sun et al., 2015)

Yanagisawa Y

The current danger level associated with GLP-1 agonist use in at-risk populations is elevated, with potential for severe consequences if not managed appropriately

Understanding why GLP-1 medications cause nauseaprimarily through delayed gastric emptyinghelps patients implement targeted management approaches

Clinical studies have demonstrated that GLP-1 drugs, including Ozempic, modulate stomach nerves, reducing muscle contractions during digestion