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Cells sense elevated viscosity through their actin cytoskeleton, which rapidly reorganizes into a dense network that polarizes and activates NHE1 [161]

[28] Thimmulappa RK, Mai KH, Srisuma S, et al

High-molecular weight HA can inhibit this inflammatory response to a certain extent by inhibiting the effects of the low-molecular weight form (71) through competition for receptors or interference with the associated signal transduction pathway (72)

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