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GSTM1 deletion prevalence: Approximately 4050% of individuals of European ancestry carry the GSTM1 null genotype, making it one of the most common functional gene deletions in the human genome

In a recent metanalysis of 12 RCTs on the effect of berberine on PCOS patients, it was reported that berberine improved reproductive hormones (TT, SHBG, LH, LH/FSH ratio), lowered fasting and post-prandial blood glucose, and improved lipid profile as compared to placebo/no treatment [13]

OReardon JP, Allison KC, Martino NS, et al

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