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Clark, I

Insulin and downstream Akt signaling also play important roles as modulators of adipose tissue growth and adipogenesis as insulin activates glucose and free fatty acid uptake, inhibits lipolysis, and de novo fatty acid synthesis in adipocytes, and induces adipogenesis [46]

A lack of intracellular cobalamin leads to reduced enzyme activity and an intracellular and subsequent systemic accumulation of methylmalonic acid (MMA), resulting in methylmalonic acidemia [29]

Insulin-stimulated glucose uptake into adipocytes occurs via insulin-mediated mobilization of GLUT4 to the plasma membrane

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Coenzyme Q10 can prevent lipid and protein peroxidation, eliminate free radicals, and reduce oxidative stress