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200 HSP90 also regulates the expression of drug resistance genes, including LRP, GST-, p53, Bcl-2, survivin, ERCC1, XRCC1, and BRCA1/2

Therefore, early and accurate diagnosis of MASH along with the assessment of liver fibrosis, is crucial for effective disease management to prevent progression to more advanced stages of liver disease [8]

This hypothesized proteolytic knockdown of components of both the thioredoxin and glutaredoxin systems is consistent with a viral strategy to inhibit DNA synthesis, to increase the pool of ribonucleotides for RNA synthesis, thereby enhancing virion production

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