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Ilyas Z, Perna S, Al-thawadi S, et al
Possible side effects GLP-1 receptor agonists can cause side effects such as nausea, vomiting, diarrhea, constipation, and abdominal pain
Other smaller studies showed mixed results
LY3463251 is the first GDF-15 agonist that has completed a phase 1 clinical trial WL was 3% after a 12-week treatment period [100]
Further research is required to comprehensively understand tirzepatides impact on vasodilation and its precise effects on cardiovascular function