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J Biol Chem 294(50):1942419435

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The absorption of vitamin B12 is fraught with hurdles: In the stomach, vitamin B12 needs to bind with a protein called Intrinsic Factor to absorb, plus sufficient acid to release it from protein foods

The role of GLP-1 in appetite and weight regulation. Nature Metabolism

What happens is that you lose your appetite and also the pleasure of eating, and so I think theres a price to be paid when you do that, Holst said

The mathematical models we developed appropriately adjust for these important factors (study differences), ensuring we truly compare 'apples with apples'