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The study was conducted in mice and the finding is mechanistically plausible given ghrelin's known orexigenic and lipogenic effects

550,551 Sudomotor dysfunction Gustatory sweating, a form of sudomotor dysfunction, is characterized by excessive sweating of the face and neck during eating, especially in response to spicy or acidic foods

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However, Oto and colleagues found that there was no significant difference in yearly height improvement between these two groups of patients (134)

instead, integrating clinical observations (to refine animal models) with preclinical investigations (to elucidate pathways) creates synergistic validation