Altogether, when administering GLP-1RA plus SGLT2i combination therapy, it is important to adopt an individualized approach to therapy taking into account individual preferences, costs and coverage, toxicity profile, consideration of kidney function and glucose-lowering efficacy, desire for weight loss, and comorbidities
How should GLP-RTbe stored
Work with your prescribing provider to understand your options, which may include transitioning to brand-name products or continuing with compounded formulations if they remain legally available through the medical necessity exemption or other regulatory pathways
However, if you are high risk for heart disease, have had a heart event or the equivalent (stroke, stent), or do not require 15-20% weight loss, semaglutide / Wegovy may be a better choice
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Obesity Affects Disease Activity and Progression, Cognitive Functioning, and Quality of Life in People With Multiple Sclerosis
