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Horm Res Paediatr 74:121128 Dimitropoulos A, Schultz RT (2008) Food-related neural circuitry in PraderWilli syndrome: response to high- versus low-calorie foods

The 7-day half-life supports once-weekly dosing and means it takes about 4-5 weeks at each dose level to reach steady state

10.1016/S0166-4328(02)00286-3 24 DicksonS

And all of it has to happen quickly enough to support real-world pharmacy operations

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The main objective of this review was to investigate the association between oxidative/nitrosative stress and recurrent pregnancy loss and to summarize existing information based on the published literature