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This mirrors studies in transplant and non-transplant populations where increases of 510 MELD-3 points over weeks to months substantially increase short-term mortality risk (D'Amico, 2005)

this offsets about 9 kg of an expected glucosuria-induced bodyweight loss of 11 kg over 2 years [77]

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Kupffer cells, the tissue resident macrophages of the liver, are activated through toll-like receptors by damage associated molecular patterns (DAMPs) released from necrotic hepatocytes