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In contrast, DPDPE is a small peptide, implying a fundamentally different mode of receptor engagement that likely involves a more localized interaction network within the transmembrane binding region

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reported that MYCN stimulates the transsulfuration pathway through the induction of the key enzymes CBS and methylthioadenosine phosphorylase, and further protects neuroblastomas from ferroptotic cell death (53)

Cheryl Bugailiskis, M.D

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