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Am J Psychiatry 158:10581066

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392,393 Many of these substances induce widespread changes in astrocyte functions, including loss of functions and dysregulated astrogliosis, which in turn may serve as comorbidities in degenerative conditions such as AD, PD, and others

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Without a loading phase, muscle creatine stores reach full saturation in approximately 3-4 weeks of daily 5-gram dosing

Proper administration was crucial to avoid mediocre results