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Retatrutide is an investigational compound currently being evaluated in Phase 2 and Phase 3 clinical trials as a potential treatment for obesity and type 2 diabetes
RYGB) for MASH-related outcomes is unclear and should be a mutual patient-physician decision Bariatric surgery is reasonable to consider in selected patients with compensated cirrhosis Simultaneous LT + SG is an emerging consideration in patients with obesity and/or MASH-related cirrhosis but requires further validation in larger studies ENDOSCOPIC BARIATRIC MODALITIES IN PRE-TRANSPLANT MASLD Endoscopic bariatric and metabolic therapies may induce weight loss, alter neurohormonal signaling, and improve insulin resistance [95]
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