glutathione makes me sick Side Effects: What to Know Glutathione with Cofactors — Seeking

In a parallel-arm, open-label human study, twelve healthy subjects ( n 6 per group) received a single oral dose of either LipoDuo or plain glutathione (1 g), and plasma glutathione levels were monitored over 24 h using LC-MS/MS

10.1007/s00726-012-1371-2 49

doi:10.1016/j.pbi.2007.01.004

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However, safety varies significantly based on individual factors including age, liver and kidney function, concurrent medications, and underlying genetic polymorphisms affecting antioxidant metabolism

Hawk SN, Lanoue L, Keen CL, Kwik-Uribe CL, Rucker RB, Uriu-Adams JY: Copper-deficient rat embryos are characterized by low superoxide dismutase activity and elevated superoxide anions