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This overactivity in GBC cells is hereby inhibited, which leads to reduced invasiveness and EMT, which is important for metastasis in cancer cells

Bennett BJ, Vallim TQ, Wang Z, Shih DM, Meng Y, Gregory J, Allayee H, Lee R, Graham M, Crooke R, Edwards PA, Hazen SL, Lusis AJ: Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation

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Approximately one-third of cases are asymptomatic ( Unlike common schwannomas, MMNST is prone to local recurrence and displays metastatic potential ( Our review on SSP-MMNST demonstrated metastasis occurrence in 31.58% of cases, with male prevalence (66.6%) and with no statistically significant difference from the metastatic rate of spinal MMNST (p=0.463) ( In 83% of cases of metastasis, the primitive tumor developed in the lumbar region with a slightly greater risk in males (RR=1.45, p=0.608)

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