Today, there is no scientific evidence that this happens, but a related drug in the class, tirzepatide (Mounjaro, Zepbound), carries warnings on its FDA labels that it may reduce the efficacy of oral hormonal contraceptives due to delayed gastric emptying. Patients are advised to switch to a non-oral form of contraception or to add a barrier method, such as condoms
doi: 10.1111/dom.13129 6 TrujilloJMNufferWEllisSL
A chart compares 2 popular weight-loss drugs, Ozempic and metformin from cost to risks and benefits Helen Marshall (2024)
Refaxing a PA request before the previous PA request has been returned will also create duplicate PA requests and may result in delays
However, tirzepatide may lead to fewer or less severe nausea symptoms compared to semaglutide, according to studies conducted by independent researchers, such as Phase 3 randomized controlled trials (RCTs) found in PubMed's electronic databases
Clinical trial data consistently shows tirzepatide producing greater average weight loss than semaglutide, though individual results vary widely