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Whereas GLP-1 monotherapy slightly reduced plasma aspartate aminotransferase (AST) levels compared with those in MK-801-treated mice, GLP-1MK-801 treatment did not affect plasma AST or alanine transaminase (ALT) levels (Extended Data Fig

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[3] [2] Clinical trials [edit] The results of Phase I safety and Phase II ascending-dose clinical trials enrolling people with obesity or type 2 diabetes were published in 2023

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Individuals with underlying health conditions, such as high blood pressure or kidney disease, should exercise caution when taking carnitine supplements

GLP-1 Agonist Medications Targeting GLP-1 has become a primary area of focus for cardiometabolic health, including weight management