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Research trends in medical sciences

Regulatory T cells in SLE: biology and use in treatment

Chronic mitochondrial ROS generation contributes to DNA damage, protein carbonylation, lipid peroxidation, and the inflammation patterns that accelerate aging across all tissue types

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Various targets (e.g., GCL, GGT, xCT, and NRF2) and compounds provide diverse avenues for modulating GSH levels, but challenges in achieving specificity and managing potential off-target effects underscore the complexity of this approach