For weight management, NICE technology appraisals TA875 (semaglutide/Wegovy) and TA664 (liraglutide/Saxenda) specify that treatment must be initiated within specialist weight management services, with specific BMI thresholds and time-limited treatment periods
Effect of continued weekly semaglutide vs withdrawal on weight loss maintenance
It's the foundation upon which all reliable data is built
Expanded obesity drug coverage can increase Medicaid spending and put pressure on overall state budgets, and states are now facing tighter budget conditions and longer-term fiscal uncertainty, due in part to the federal Medicaid cuts in the 2025 reconciliation law, causing state Medicaid programs to re-evaluate their obesity drug coverage
If taken with insulin or an insulin secretagogue (e.g., sulfonylurea), it is best to talk to your health care provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia
OCULAR ADVERSE EFFECTS Other cancers Recent investigations have highlighted the association between various neoplasms, such as thyroid, breast, and cholangiocarcinoma, and GLP-1 RAs [105-107]
