In this situation, it can be challenging to demonstrate B12 deficiency even when there are typical symptoms (including neuropathy-like paraesthesia and numbness), as serum B12 concentrations may be just within, or sometimes above, the normal range due to the oral supplementation
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[32], UDCA (Ursodeoxycholic Acid) therapy at a dose of 2835 mg/kg per day significantly reduced ALT activity compared to placebo: 28.3 and 1.6%, respectively ( P 0.05, Table 2, F = 3.83)
This unusual bell-shaped dose response curve suggests the peptide operates through mechanisms that remain effective even at very low concentrations