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The pH and ionic strength of the hydration buffer also influence protein charge and folding stability

Lancet Gastroenterol Hepatol 5(11):9961007 Saab S, Suraweera D, Au J, Saab EG, Alper TS, Tong MJ (2016) Probiotics are helpful in hepatic encephalopathy: a meta-analysis of randomized trials

doi: 10.1039/C8RA10029B 103 ZhuY.LiY.XuY.ZhangJ.MaL.QiQ.et al

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In this context, SHMT1 knockdown leads to impaired migratory ability, due to increased ROS levels, reduced ATP generation, and AMPK activation, affecting cytoskeleton remodeling [118]