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GI Status: Minimal side effects

Do not freeze, and protect it from light

Endocrine, 87(1), 159-169

Gut dysbiosis is a disruption in healthy gut microbial balance, promoting CRC through inflammation, impaired barrier function, and altered nutrient processing and mucosal integrity

Metformin remains the first-line oral agent for most patients with type 2 diabetes, unless contraindicated, and should be continued alongside any alternative therapy unless there are specific reasons for discontinuation, as recommended by NICE

Adipokines such as leptin and adiponectin are involved in IR ( Disordered glucose metabolism is closely linked to the severity of AP