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Overexpression of GLP-1Rs in the LS also did not change oxygen uptake (VO 2 ), carbon dioxide discharge (VCO 2 ), respiratory exchange ratio, and average energy expenditure (Supplemental Figure 5, IP)

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This study was designed to compare the endocrine and metabolic parameters as well as subjective and objective measures of stress in women with PCOS before and after treatment with acetyl-l-carnitine (ALC) and metformin plus pioglitazone