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Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a highly selective thyroid hormone receptor agonist in clinical trials for the treatment of dyslipidemia

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The results showed that the biological activity of AXA1125 was greater in patients with T2D, compared with placebo