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Slowed Gastric Emptying: GLP-1 slows down the rate at which food leaves the stomach and enters the small intestine

In the STEP-1 trial, 1,961 patients were followed for 68 weeks and underwent randomization to semaglutide or placebo plus lifestyle intervention resulting in14.9% weight loss in the semaglutide group versus 2.5% in the placebo group [33]

Dietary and lifestyle adjustments: Eat smaller, more frequent meals rather than large portions, which can exacerbate delayed gastric emptying Avoid foods and drinks known to trigger reflux, including fatty or spicy foods, caffeine, alcohol, and carbonated beverages Remain upright for at least two to three hours after eating

A: If you have Type 2 diabetes, you may be able to after you discuss this with your doctor

Impure peptide preparations can introduce experimental confounders, as degradation products or synthesis byproducts may have their own biological activities or interfere with receptor binding assays

Provider guidance is essential for evidence-based choice